Actinidin Active

A clinically relevant enzyme for gut health innovation

The richest natural actinidin extract from New Zealand kiwifruit, optimised for gut health formulations.

Standardised enzyme activity level range 190 - 230 units/g.

Protein Digestion

Gut Microbiome Balance

Prebiotic Functionality

Natural Enzyme

Why Gut Health Needs Actinidin

Modern diets often leave proteins undigested, which can impact comfort, nutrient uptake, and overall gut health.

Actinidin Active® provides a natural multifunctional solution - enhancing digestion, nourishing the gut microbiome, and supporting the body's ability to absorb and use nutrients.

Efficient Protein Digestion

Actinidin Active® naturally breaks down proteins, supporting digestion and reducing gastrointestinal discomfort.

Microbiome Support

Prebiotics and fibres in Actinidin Active® nourish beneficial gut microbes and support gut barrier integrity.

Nutrient Absorption

Enhanced protein digestion and a balanced microbiome increase the uptake of beneficial nutrients.

Actinidin is a natural proteolytic enzyme uniquely found in kiwifruit, with a structure and activity profiled that complements human digestive enzymes. Actinidin operates effectively across a broad pH range, initiating protein breakdown in the stomach and continuing into the small intestine. This enhances the cleavage of complex protein chains into absorbable peptides and amino acids, improving overall protein bioavailability.

Actinidin accelerates the digestion of both animal and plant proteins, including casein, collagen, and soy proteins. Formulations containing Actindin Active® can reduce gastrointestinal discomfort associated with incomplete protein digestion, such as bloating and flatulence, while maximising nutrient absorption.

By integrating Actinidin Active® into supplements or functional foods, product developers can deliver a scientifically-baked solution that supports digestive efficiency naturally.

Protein digestion is closely linked to gut microbiome health. Undigested proteins that reach the colon can be metabolised by opportunistic bacteria, potentially producing metabolites that disrupt homeostasis. Actinidin Active® assists protein breakdown, reducing the substrate for harmful bacterial fermentation.

In addition, kiwifruit naturally contains soluble fibres and prebiotic compounds which are retained in Actinidin Active®. These prebiotics and fibres serve as a food source for beneficial bacteria, stimulating their growth and activity. This combination of enzymatic protein digestion and prebiotic support creates a gut environment conducive to beneficial microbial populations, enhancing short-chain fatty acid (SCFA) production, maintaining gut barrier integrity, and supporting overall immune function.

Actinidin Active® is not only a digestible aid, but also an ingredient that promotes gut microbiome balance naturally, combining enzymatic activity with the inherent prebiotic and fibre benefits of kiwifruit.

Actinidin Active® enhances the bioavailability of essential amino acids and other nutrients by improving protein digestion in the stomach and small intestine. More complete protein breakdown ensures that critical building blocks for muscle synthesis, enzymatic activity, and metabolic function are efficiently absorbed.

Beyond proteins, the fibres and prebiotics naturally present in kiwifruit further optimise nutrient utilisation by supporting beneficial bacteria. These microbes produce SCFAs and vitamins, which contribute to gut barrier integrity and systemic nutrient absorption. The combined enzymatic and prebiotic effects ensure that nutrients from both proteins and other dietary components are effectively delivered to the body.

Immune Support – SCFAs from fibre and prebiotic fermentation help regulate inflammation and maintain gut barrier strength.
Glycemic Control – Soluble fibres form a gel-like matrix that slows sugar absorption, supporting stable blood glucose levels.
Cardiovascular Health – Kiwifruit bioactives may reduce platelet aggregation and blood triglycerides, contributing to heart health.

Applications for Product Developers

Versatile for Nutraceuticals

Actinidin Active® is versatile across a wide range of applications - whether formulated as a health supplement in tablets, capsules, or gummies, or blended into a green drink to support digestion. It's potential expands beyond supplements - its properties can also be harnessed for healthier, more vibrant skin. The opportunities for application continue to grow.